{"id":1122,"date":"2019-04-22T07:27:33","date_gmt":"2019-04-22T07:27:33","guid":{"rendered":"https:\/\/albayan.edu.iq\/en\/?p=1122"},"modified":"2019-04-22T07:27:33","modified_gmt":"2019-04-22T07:27:33","slug":"hyaluronidase-co-administration-with-oncolytic-newcastle-disease-virus-enhances-its-antitumor-efficacy-in-mice-mammary-adenocarcinoma","status":"publish","type":"post","link":"https:\/\/albayan.edu.iq\/en\/2019\/04\/22\/1122\/","title":{"rendered":"Hyaluronidase Co-administration with Oncolytic Newcastle Disease Virus Enhances Its Antitumor Efficacy in Mice Mammary Adenocarcinoma"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>Hasanain Sahib<\/strong>,\u00a0<strong>Ahmed Majeed Al-Shammari<\/strong>, <strong>Bahaa Abdullah Al-Rubaii<\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>Abstract<\/strong><\/p>\n<p style=\"text-align: justify;\"><strong>Purpose:<\/strong>codelivery evaluation of\u00a0the of ovine hyaluronidase enzyme with oncolytic Newcastle Disease Virus\u00a0 to determine spreading\u00a0 of the virus throughout Adenocarcinoma\u00a0 tumors Models in mice, thereby leading to a greater overall antitumor efficacy in tumor models.<\/p>\n<p style=\"text-align: justify;\">This study aimed to determine the effectiveness of Combination effect between Ovine origin Hyaluronidase and Newcastle Disease Virus and compare the invasion of oncolytic virus in combination with Hyaluronidase enzyme with oncolytic virus only.<\/p>\n<p style=\"text-align: justify;\">Experimental Design: the ovine hyaluronidase dose that cooadminstrated with 6.5&#215;10<sup>5<\/sup>virus concentration per mi was 200 international unit that provided best invasion efficiency and spread of Newcastle disease virus within tumors that detected through the immunofluorescence assay. was combined with oncolytic viruses in tumor models to determine whether the combination treatment results in an improvement of antitumor efficacy.<\/p>\n<p style=\"text-align: justify;\"><strong>For full article click the link below:<\/strong><\/p>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/www.researchgate.net\/publication\/331075531_Intratumoral_Co-Administration_of_Oncolytic_Newcastle_Disease_Virus_and_Bacterial_Hyaluronidase_Enhances_Virus_Potency_in_Tumor_Models\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.researchgate.net\/publication\/331075531<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hasanain Sahib,\u00a0Ahmed Majeed Al-Shammari, Bahaa Abdullah Al-Rubaii Abstract Purpose:codelivery evaluation of\u00a0the of ovine hyaluronidase enzyme with oncolytic Newcastle Disease Virus\u00a0 to determine spreading\u00a0 of the virus throughout Adenocarcinoma\u00a0 tumors Models in mice, thereby leading to a greater overall antitumor efficacy in tumor models. This study aimed to determine the effectiveness of Combination effect between Ovine origin Hyaluronidase and Newcastle Disease Virus and compare the invasion of oncolytic virus in combination with Hyaluronidase enzyme with oncolytic virus only. Experimental Design: the ovine hyaluronidase dose that cooadminstrated with 6.5&#215;105virus concentration per mi was 200 international unit that provided best invasion efficiency and spread <a href=\"https:\/\/albayan.edu.iq\/en\/2019\/04\/22\/1122\/\"> [&#8230;]<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[26],"tags":[27],"class_list":["post-1122","post","type-post","status-publish","format-standard","hentry","category-staff-researches","tag-staff-researches"],"jetpack_featured_media_url":"","jetpack_shortlink":"https:\/\/wp.me\/paQN8v-i6","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/posts\/1122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/comments?post=1122"}],"version-history":[{"count":2,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/posts\/1122\/revisions"}],"predecessor-version":[{"id":1126,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/posts\/1122\/revisions\/1126"}],"wp:attachment":[{"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/media?parent=1122"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/categories?post=1122"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/tags?post=1122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}