The student (Esra Hussein Ali) discussed her master’s thesis at the college of Pharmacy \/ Mustansiriya University entitled (Evaluation of the effect of metformin against the symptoms of Parkinson’s induced by rotenone in a rat model)<\/p>\n
The main objective of the study was to find out the motor and non-motor symptoms with the effect of metformin treatment in the presence and supervision of the dean of the college of Health and Medical Techniques (Prof.Dr.Ghaith Ali Jasim al-Zubaidi).
\nThe results demonstrate that metformin may be a modulating agent for Parkinson’s disease by targeting several disease pathways .
\nThe results of the study found that metformin therapy led to a clear improvement in motor performance and reduced oxidative stress with inhibition of the effectiveness of TLR4 and GSK3\u03b2 and reduced levels of \u03b1-synuclein and DDC, indicating its anti-inflammatory and neuronal protective effect.
\nThe combination of metformin and L-DOPA (basic therapy) had the effect of a greater improvement in both behavior and molecular data.<\/p>\n","protected":false},"excerpt":{"rendered":"
The student (Esra Hussein Ali) discussed her master’s thesis at the college of Pharmacy \/ Mustansiriya University entitled (Evaluation of the effect of metformin against the symptoms of Parkinson’s induced by rotenone in a rat model) The main objective of the study was to find out the motor and non-motor symptoms with the effect of metformin treatment in the presence and supervision of the dean of the college of Health and Medical Techniques (Prof.Dr.Ghaith Ali Jasim al-Zubaidi). The results demonstrate that metformin may be a modulating agent for Parkinson’s disease by targeting several disease pathways . The results of the study […]<\/a><\/p>\n","protected":false},"author":1,"featured_media":4377,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[14],"tags":[34],"class_list":["post-4376","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-news","tag-pathological-news"],"jetpack_featured_media_url":"https:\/\/albayan.edu.iq\/en\/wp-content\/uploads\/2025\/09\/WhatsApp-Image-2025-08-29-at-17.57.35-1.jpeg","jetpack_shortlink":"https:\/\/wp.me\/paQN8v-18A","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/posts\/4376","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/comments?post=4376"}],"version-history":[{"count":1,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/posts\/4376\/revisions"}],"predecessor-version":[{"id":4379,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/posts\/4376\/revisions\/4379"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/media\/4377"}],"wp:attachment":[{"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/media?parent=4376"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/categories?post=4376"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/albayan.edu.iq\/en\/wp-json\/wp\/v2\/tags?post=4376"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}