Hasanain Sahib, Ahmed Majeed Al-Shammari, Bahaa Abdullah Al-Rubaii Abstract Purpose:codelivery evaluation of the of ovine hyaluronidase enzyme with oncolytic Newcastle Disease Virus  to determine spreading  of the virus throughout Adenocarcinoma  tumors Models in mice, thereby leading to a greater overall antitumor efficacy in tumor models. This study aimed to determine the effectiveness of Combination effect between Ovine origin Hyaluronidase and Newcastle Disease Virus and compare the invasion of oncolytic virus in combination with Hyaluronidase enzyme with oncolytic virus only. Experimental Design: the ovine hyaluronidase dose that cooadminstrated with 6.5x105virus concentration per mi was 200 international unit that provided best invasion efficiency and spread [...]

RAFAL SALAM KADHIM  and  ALYA KHIDER ABBAS Abstract The synthesis, structural spectroscopic properties of 4-(2-benzimidazolylazo)proline (BMP) and its complexes derived from [Cu(II), Ag(I) and Au(III)] salts were done. The mode of bonding for the complexes were accomplished based on elemental analysis, FTIR, UV-Vis and HNMR spectroscopy, magnetic measurement and molar conductivity. It has been found that the ligand (BMP) behaves as N,N-neutral bidentate which was forming chelates with molar ratio (1:2) (M:L) stoichiometry for [Cu(II) and Ag(I)] while Au(III) complex form molar ratio (1:1) at optimum concentration and pH as well as (lmax). The stability constant and Gibbs free energy for [...]

Mervet A. Mshachal MSc, Thaanaa R. Abdulrahman PhD, Mahmoud S. Khudair FIBMS, Jabbar S. Hassan PhD   Abstract Background Acinetobacter baumannii (A. baumanii) has recently emerged as a major pathogen causing nosocomial infections in patients admitted to intensive care units with a surprisingly rapid acquisition of antibiotic resistance. Objective To study the rate of occurrence of A. baumanii isolated from different clinical specimens and to study the rate of occurrence of multidrug resistance especially NDM-1 and qnrA genes. Methods A total of sixty-two (62) clinical isolates of A. baumanii were tested against 14 antibiotics by disc diffusion method. Minimum inhibitory concentration [...]

Assistant Lecturer Fathaa Abdulaah Mahmoud The present study aimed to investigate the effect of cryptococcal sonicated antigen and chitosan on the infection with this fungus which isolated from human skin lesions. In order to achieve  this goal, usage of  Cryptococcusneoformansisolate which was isolated from human skin lesion in order to prepare the sonicated antigen also  60 white mice from  both sexes, at average age 8-10 weeks were getted and divided randomly into 4 groups equally and treated as following: fifteen (15) mice were immunized with 0.5ml of WSC Ags (protein concentration14mg/ml )S/C two doses ,one week interval. fifteen (15) mice were [...]

Assistant Lecturer Adil A. Merza  Abstract: Sex hormone-binding globulin (SHBG) is a key regulator of the actions of anabolic steroids. Chronic heart failure (HF) has been associated with anabolic steroid deficiency, The present study to assess the role of SHBG and sex hormones in patient with heart failure so as to it may be had importance for diagnostic and progression of heart failure.The study involved an 80 men (age range 45-69 years), 40 men had HF (i.e. left ventricular ejection fraction [LVEF] <40%) and the other 40 men considered as the control group. The patients were selected from Ibn-Alnafis and Baghdad [...]